Synthesis and pharmacological evaluation of indole-based sigma receptor ligands

DOI: 10.1016/j.ejmech.2011.08.031

Source and publish data:

European Journal of Medicinal Chemistry p. 5154 - 5161 (2011)

Update date:2022-08-03

Topics:

Authors:

Mésangeau, Christophe

Amata, Emanuele

Alsharif, Walid

Seminerio, Michael J.

Robson, Matthew J.

Matsumoto, Rae R.

Poupaert, Jacques H.

McCurdy, Christopher R.

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Article abstract of DOI:10.1016/j.ejmech.2011.08.031

A series of novel indole-based analogs were prepared and their affinities for sigma receptors were determined using in vitro radioligand binding assays. The results of this study identified several compounds with nanomolar sigma-2 affinity and significant

Full text of DOI:10.1016/j.ejmech.2011.08.031

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