1122090-50-9

Basic information

• Product Name: Ethyl 6-chloro-4-methylpyridine-2-carboxylate
• Synonyms: Ethyl 6-chloro-4-methylpicolinate;6-Chloro-4-methyl-2-pyridinecarboxylic acid ethyl ester;Ethyl 6-chloro-4-methylpyridine-2-carboxylate;Methyl 6-chloro-4-Methylpyridine-2-carboxylate
• CAS NO: 1122090-50-9
• Molecular Formula: C9H10ClNO2
• Molecular Weight: 199.6342
• Product Categories: Heterocycle-Pyridine series
• Mol File: 1122090-50-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 311.538 °C at 760 mmHg
• Flash Point: 142.213 °C
• Appearance: /
• Density: 1.208 g/cm³
• CAS DataBase Reference: Ethyl 6-chloro-4-methylpyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 6-chloro-4-methylpyridine-2-carboxylate(1122090-50-9)
• EPA Substance Registry System: Ethyl 6-chloro-4-methylpyridine-2-carboxylate(1122090-50-9)

Safety Data

• Hazardous Substances Data: 1122090-50-9(Hazardous Substances Data)

Usage

General Description

Ethyl 6-chloro-4-methylpyridine-2-carboxylate is a chemical compound with the molecular formula C8H8ClNO2. It comes under the class of organic compounds known as pyridinecarboxylic acids and derivatives. Pyridines are compounds with a pyridine ring, a six-membered aromatic heterocycle which consists of two nitrogen atoms and four carbon atoms, to which a carboxyl group is attached. As per its name, this chemical has a chlorine atom attached to the 6th carbon and a methyl group attached to the 4th carbon of the pyridine ring. It is typically in the form of a white solid and finds potential application in the field of chemical research. It is known with the IUPAC name Ethyl 6-chloro-4-methylpyridine-2-carboxylate, but might also have other synonyms.

Upstream product

• 324028-95-7 6-chloro-4-methylpyridine-2-carboxylic acid 
• 64-17-5 ethanol 
• 1122090-46-3 6-chloro-4-methyl-2-vinylpyridine 
• 1122090-48-5 potassium 6-chloro-4-methylpyridine-2-carboxylic acid 

Downstream Products

• 1227606-30-5 2-chloro-6-(chloromethyl)-4-methyl-pyridine 

Relevant articles and documents

3-SUBSTITUTED PIPERIDINE COMPOUNDS FOR CBL-B INHIBITION, AND USE OF A CBL-B INHIBITOR IN COMBINATION WITH A CANCER VACCINE AND/OR ONCOLYTIC VIRUS

Compounds, compositions, and methods for use in inhibiting the E3 enzyme Cbl-b in the ubiquitin proteasome pathway are disclosed. The compounds, compositions, and methods can be used to modulate the immune system, to treat diseases amenable to immune system modulation, and for treatment of cells in vivo, in vitro, or ex vivo. Also disclosed are pharmaceutical compositions comprising a Cbl-b inhibitor and a cancer vaccine, as well as methods for treating cancer using a Cbl-b inhibitor and a cancer vaccine; and pharmaceutical compositions comprising a Cbl-b inhibitor and an oncolytic virus, as well as methods for treating cancer using a Cbl-b inhibitor and an oncolytic virus.

NOVEL PYRIMIDINE-PYRIDINE DERIVATIVES

The invention relates to novel pyrimidine-pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS

The invention relates to pyridine derivatives of Formula (I), wherein A, R1, R2, R3, R4, R5, R6 and R7 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.