112221-46-2Relevant academic research and scientific papers
Synthesis, Activity, and Molecular Modeling Studies of Novel Human Aldose Reductase Inhibitors Based on a Marine Natural Product
De La Fuente, Jesús ángel,Manzanaro, Sonia,Martín, María Jesús,De Quesada, Teresa G.,Reymundo, Isabel,Luengo, Santos M.,Gago, Federico
, p. 5208 - 5221 (2007/10/03)
Aldose reductase (ALR2) has been implicated in the etiology of diabetic complications, including blindness. Because of the limited number of currently available drugs for the prevention of these long-term complications, the discovery of new ALR2 inhibitor
