112221-61-1Relevant academic research and scientific papers
Synthesis, Activity, and Molecular Modeling Studies of Novel Human Aldose Reductase Inhibitors Based on a Marine Natural Product
De La Fuente, Jesús ángel,Manzanaro, Sonia,Martín, María Jesús,De Quesada, Teresa G.,Reymundo, Isabel,Luengo, Santos M.,Gago, Federico
, p. 5208 - 5221 (2007/10/03)
Aldose reductase (ALR2) has been implicated in the etiology of diabetic complications, including blindness. Because of the limited number of currently available drugs for the prevention of these long-term complications, the discovery of new ALR2 inhibitor
Antibiotics from Algae, 38. - Base-Catalyzed Reactions of Multiple Hydroxylated Diphenyl Ethers
Glombitza, Karl-Werner,Woelwer-Rieck, Ursula
, p. 261 - 266 (2007/10/02)
Diphenyl ethers are in general difficult to cleave.Under certain conditions in a weak alkaline aqueous solution multiple hydroxylated diphenyl ethers are brought to reaction.It is shown at 33 model substances which substitution pattern must be present in
