112238-16-1 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
(Z)-3-Amino-3-(3,4-dimethoxyphenyl)acrylonitrile is used as an intermediate in the synthesis of various pharmaceuticals and biologically active compounds. Its potential biological activities make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (Z)-3-Amino-3-(3,4-dimethoxyphenyl)acrylonitrile is utilized as a key component in the design and synthesis of novel compounds with potential therapeutic applications. Its unique structure allows for the exploration of new chemical space and the discovery of innovative drug candidates.
Used in Chemical Research:
(Z)-3-Amino-3-(3,4-dimethoxyphenyl)acrylonitrile serves as a valuable target for chemical research, enabling scientists to study its reactivity, properties, and potential applications in various chemical reactions and processes. This research can lead to the development of new synthetic methods and the discovery of novel compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 112238-16-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,2,3 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 112238-16:
(8*1)+(7*1)+(6*2)+(5*2)+(4*3)+(3*8)+(2*1)+(1*6)=81
81 % 10 = 1
So 112238-16-1 is a valid CAS Registry Number.
112238-16-1Relevant academic research and scientific papers
Pyrrole as a Directing Group: Regioselective Pd(II)-Catalyzed Alkylation and Benzylation at the Benzene Core of 2-Phenylpyrroles
Wiest, Johannes M.,P?thig, Alexander,Bach, Thorsten
supporting information, p. 852 - 855 (2016/03/04)
Pyrrole has been employed for the first time as a directing group in the Pd(II)-catalyzed ortho-functionalization of C(sp2)-H bonds. A variety of substituted 2-phenylpyrroles were successfully methylated, alkylated, or benzylated in the ortho-position of the benzene ring, yielding the respective 2-substituted pyrrol-2-yl benzenes (36 examples, 51-93% yield). Neither additives nor additional ligands were required to perform the reaction, which was routinely conducted with PdBr2 as the catalyst and Li2CO3 as the base. Mechanistically, there is evidence that precoordination of palladium to the pyrrole enables the regioselective ortho-attack. (Chemical Equation Presented).
Synthesis of 6-(3,4-Dimethoxyphenyl)-4-oxo-3,4-dihydrobenzonaphthyridin-6-ium Chloride (Perloline Chloride)
Ridley, Anne B.,Taylor, Walter C.
, p. 631 - 634 (2007/10/02)
Perloline was synthesized as its chloride, 6-(3,4-dimethoxyphenyl)-4-oxo-3,4-dihydrobenzonaphthyridin-6-ium chloride (1b), by utilizing the photochemical rearrangement of the N-oxide (6) of 5-(3,4-dimethoxyphenyl)benzonaphthyridin-4(3H)-on
