112246-74-9 Usage
Uses
Used in Pharmaceutical Industry:
(+)-DIP-BROMIDE(TM) is used as a chiral catalyst for asymmetric DIels-Alder reactions. This application is significant because it allows for the selective synthesis of specific enantiomers, which are crucial in the development of drugs with desired biological activities and reduced side effects.
Used in Organic Synthesis:
(+)-DIP-BROMIDE(TM) is also used as a catalyst in the Pictet-Spengler reaction, a type of organic reaction that involves the cyclization of a primary amine with an aldehyde or ketone to form a tetrahydroisoquinoline. This reaction is important in the synthesis of various natural products and pharmaceutical compounds, making (+)-DIP-BROMIDE(TM) a valuable tool in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 112246-74-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,2,4 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 112246-74:
(8*1)+(7*1)+(6*2)+(5*2)+(4*4)+(3*6)+(2*7)+(1*4)=89
89 % 10 = 9
So 112246-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H34BBr/c1-11-15-7-13(19(15,3)4)9-17(11)21(22)18-10-14-8-16(12(18)2)20(14,5)6/h11-18H,7-10H2,1-6H3/t11-,12-,13?,14?,15?,16?,17-,18-/m0/s1
112246-74-9Relevant academic research and scientific papers
Enantioselective Ring Cleavage of meso-Epoxides with B-Halodiisopinocampheylboranes
Joshi, N. N.,Srebnik, M.,Brown, Herbert C.
, p. 6246 - 6248 (2007/10/02)
Asymmetric synthesis starting from meso compounds is an increasingly important method for the preparation of optically active compound.We now report the synthesis of optically active 1,2-halohydrins using B-halodiisopinocampheylboranes, Ipc2BX (1a-c).
