112255-11-5

Upstream product

• 917-54-4 methyllithium 
• 101155-69-5 methyl 2,3-dideoxy-6-o-trityl-α-D-glycero-hex-2-enopyranosid-4-ulose 
• 94616-84-9 dichloromethylcerium 

Downstream Products

• 79607-37-7 methyl 3,4-dideoxy-4-c-methyl-6-o-trityl-α-D-glycero-hex-3-enopyranosid-2-ulose 
• 101155-65-1 methyl 2,3-di-O-acetyl-4-deoxy-4,4-di-C-methyl-6-O-trityl-α-D-arabino-hexopyranoside 
• 101155-64-0 methyl 2,3-di-O-acetyl-4-deoxy-4,4-di-C-methyl-6-O-trityl-α-D-xylo-hexopyranoside 
• 101155-63-9 methyl 3,4-dideoxy-4,4-di-C-methyl-2-O-trimethylsilyl-6-O-trityl-α-D-glycero-hex-2-enopyranoside 
• 101155-62-8 methyl 3,4-dideoxy-4,4-di-C-methyl-6-O-trityl-α-D-glycero-hexopyranosid-2-ulose 

Relevant academic research and scientific papers

Rection of Enohexopyranoside Acetates with Lithium Dimethylcuprate(I) and Its Application to Synthesis of Prelog-Djerassi Lactone

In the reaction of two 2-O-acetyl-3-enohexopyranosides and four 4-O-acetyl-2-enohexopyranosides including 2-C-methyl and 4-C methyl derivatives, respectively, with lithium dimethylcuprate(I), anti SN2' substitution was proved to be preferential, giving the corresponding C-methylated derivatives.On the other hand, SN2 substitution occurred in the reaction of the 2-enopyranoside without methyl branch and D-glucal triacetate

TWO COMPLEMENTARY METHODS FOR INTRODUCTION OF gem-DIMETHYL GROUP IN HEXOPYRANOSIDE RING

Hexopyranosides having a gem-dimethyl group in the pyranose ring were synthesized by reductive cleavage of spiro-cyclopropane derivatives and by addition of methyl cuprates to methyl-branched enolone derivatives.