79607-37-7

Upstream product

• 101155-69-5 methyl 2,3-dideoxy-6-o-trityl-α-D-glycero-hex-2-enopyranosid-4-ulose 
• 111828-63-8 (2R,3S,6S)-6-Methoxy-3-methyl-2-trityloxymethyl-3,6-dihydro-2H-pyran-3-ol 
• 111828-63-8 (2R,6S)-6-Methoxy-3-methyl-2-trityloxymethyl-3,6-dihydro-2H-pyran-3-ol 

Downstream Products

• 69056-12-8 (+)-Prelog-Djerassi lactonic acid 
• 73656-98-1 (2S,5S,6S)-2-Methoxy-5-methyl-3-methylene-6-trityloxymethyl-tetrahydro-pyran 
• 79646-63-2 methyl 2,3,4-trideoxy-2,3-di-C-methyl-6-O-trityl-α-D-ribo-hexopyranoside 
• 79646-64-3 methyl 2,3,4-trideoxy-2,4-di-C-methyl-α-D-arabino-hexopyranoside 
• 101155-65-1 methyl 2,3-di-O-acetyl-4-deoxy-4,4-di-C-methyl-6-O-trityl-α-D-arabino-hexopyranoside 
• 101155-64-0 methyl 2,3-di-O-acetyl-4-deoxy-4,4-di-C-methyl-6-O-trityl-α-D-xylo-hexopyranoside 
• 101155-62-8 methyl 3,4-dideoxy-4,4-di-C-methyl-6-O-trityl-α-D-glycero-hexopyranosid-2-ulose 
• 79607-38-8 (2S,5S,6S)-2-Methoxy-5-methyl-6-trityloxymethyl-dihydro-pyran-3-one 
• 101155-63-9 methyl 3,4-dideoxy-4,4-di-C-methyl-2-O-trimethylsilyl-6-O-trityl-α-D-glycero-hex-2-enopyranoside 
• 79607-39-9 (2S,6S)-2-Methoxy-5-methyl-3-methylene-6-trityloxymethyl-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Synthesis of 2,2-Di-C-methyl-2-deoxy- and 4,4-Di-C-methyl-4-deoxypyranosides via Michael Addition of Conjugated Enopyranosiduloses

Three hexopyranosides having gem-di-C-methyl group at 2- or 4-positions were synthesized by Michael addition to 2-enopyranosid-4-ulose and 3-enopyranosid-2-ulose derivatives, respectively, followed by hydroboration.A heptopyranosid-6-ulose having gem-di-C-methyl group at C-4 was also synthesized from 4-enopyranosid-6-ulose derivative in a similar way.

TWO COMPLEMENTARY METHODS FOR INTRODUCTION OF gem-DIMETHYL GROUP IN HEXOPYRANOSIDE RING

Hexopyranosides having a gem-dimethyl group in the pyranose ring were synthesized by reductive cleavage of spiro-cyclopropane derivatives and by addition of methyl cuprates to methyl-branched enolone derivatives.