112260-64-7

Upstream product

• 112260-62-5 Methanesulfonic acid (4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 41167-51-5 (4S,5S)-4-hydroxymethyl-2,2,5-trimethyl-[1,3]-dioxolane 
• 70831-49-1 (4S,5S)-4-hydroxymethyl-2,2-dimethyl-5-tosyloxymethyl-1,3-dioxolane 
• 50622-09-8 2,3-O-isopropylidene-L-threitol 
• 37031-29-1 (-)-dimethy-2,3-O-isopropylidene-L-tartrate 
• 112260-63-6 (4S,5S)-4-(iodomethyl)-2,2,5-trimethyl-1,3-dioxolane 
• 603-35-0 triphenylphosphine 

Relevant academic research and scientific papers

Preparation of (4R,5S)-(5-methyl-2,2-dimethyl-1,3-dioxolane-4-ylmethyl)-phosphonium iodide. A synthetic approach to olguine: further model studies

The enantiomerically pure title compound ((4R,5S)-(5-methyl-2,2-dimethyl-1,3-dioxolane-4-ylmethyl)-phosphonium iodide) has been synthesized starting from (R,R)-(+)-tartaric acid.The synthesis of an oliguine analog has been carried out.Attempts have been made to improve the stereoselectivity and yield of key steps.