Isonicotinic acid hydrazide, also known as isoniazid, is a hydrazide derivative of isonicotinic acid, with the chemical formula C6H7N2O. It is a white crystalline powder that is soluble in water and has a melting point of 170-172°C. Isoniazid is primarily used as a first-line antituberculosis drug, targeting the enzyme enoyl-ACP reductase, which is crucial for the synthesis of mycolic acids in the cell wall of Mycobacterium tuberculosis. The hydrochloride salt form of isoniazid, isoniazid hydrochloride, is a white to off-white crystalline powder with the chemical formula C6H8ClN2O. It is also used as an antituberculosis agent and is often preferred due to its increased solubility and stability compared to the free base form. Both forms of the drug are essential in the treatment of tuberculosis, either as monotherapy or in combination with other antituberculosis medications.
The CAS Registry Mumber 1123-87-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 3 respectively; the second part has 2 digits, 8 and 7 respectively. Calculate Digit Verification of CAS Registry Number 1123-87: (6*1)+(5*1)+(4*2)+(3*3)+(2*8)+(1*7)=51 51 % 10 = 1 So 1123-87-1 is a valid CAS Registry Number.