4427-16-1

Basic information

• Product Name: N-(diaminomethylideneamino)pyridine-4-carboxamide
• Synonyms: N-(diaminomethylideneamino)pyridine-4-carboxamide
• CAS NO: 4427-16-1
• Molecular Formula: C₇H₉N₅O
• Molecular Weight: 179.18
• Mol File: 4427-16-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(diaminomethylideneamino)pyridine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(diaminomethylideneamino)pyridine-4-carboxamide(4427-16-1)
• EPA Substance Registry System: N-(diaminomethylideneamino)pyridine-4-carboxamide(4427-16-1)

Safety Data

• Hazardous Substances Data: 4427-16-1(Hazardous Substances Data)

Upstream product

• 420-04-2 CYANAMID 
• 1123-87-1 isonicotinic acid hydrazide; hydrochloride 
• 54-85-3 isoniazid 
• 14527-26-5 2-methylisothiourea sulphate 
• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 1937-19-5 1-aminoguanidine hydrochloride 

Downstream Products

• 3652-17-3 3-(pyridin-4-yl)-1H-1,2,4-triazol-5-amine 
• 3652-17-3 5-(pyridin-4-yl)-1H-1,2,4-triazol-3-amine 

Relevant articles and documents

Triazole derivative and pharmaceutical use thereof

An agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, an agent for the prophylaxis and treatment of allergic diseases, an agent for the prophylaxis and treatment of eosinophil-related diseases and an eosinophilia inhibitor, comprising, as an active ingredient, a series of triazole derivatives of the following formula (I) STR1 or the following formula (III) STR2 wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. A novel monocyclic or bicyclic triazole derivative. The agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, the agent for the prophylaxis and treatment of allergic diseases, the agent for the prophylaxis and treatment of eosinophil-related diseases, the eosinophilia inhibitor and the novel triazole derivative of the present invention all, have superior eosinophilia-inhibitory action and lymphocyte activation-inhibitory action. They are low toxic and persistent in action. They are particularly effective in the treatment of accumulation and activation of eosinophil and lymphocytes, inflammatory respiratory tract diseases, eosinophil-related diseases such as eosinophilia, and immune-related diseases.