1123307-53-8

Basic information

• Product Name: BenzenesulfonaMide, 2,5-dibroMo-N-[(3R,5S)-1-cyano-5-Methyl-3-pyrrolidinyl]-
• Synonyms: BenzenesulfonaMide, 2,5-dibroMo-N-[(3R,5S)-1-cyano-5-Methyl-3-pyrrolidinyl]-;2,5-dibromo-N-[(3R,5S)-1-cyano-5-methylpyrrolidin-3-yl]benzenesulfonamide
• CAS NO: 1123307-53-8
• Molecular Formula: C₁₂H₁₃Br₂N₃O₂S
• Molecular Weight: 423.12352
• Mol File: 1123307-53-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BenzenesulfonaMide, 2,5-dibroMo-N-[(3R,5S)-1-cyano-5-Methyl-3-pyrrolidinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzenesulfonaMide, 2,5-dibroMo-N-[(3R,5S)-1-cyano-5-Methyl-3-pyrrolidinyl]-(1123307-53-8)
• EPA Substance Registry System: BenzenesulfonaMide, 2,5-dibroMo-N-[(3R,5S)-1-cyano-5-Methyl-3-pyrrolidinyl]-(1123307-53-8)

Safety Data

• Hazardous Substances Data: 1123307-53-8(Hazardous Substances Data)

Upstream product

• 477293-60-0 (2S,4S)-4-hydroxy-2-methylpyrrolidine-1-carboxylic acid tert-butyl ester 
• 134441-72-8 1,1-dimethylethyl (2R,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate 
• 3398-22-9 trans-4-hydroxyproline 
• 178962-09-9 methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate 
• 135042-17-0 (2R,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 
• 506-68-3 bromocyane 
• 1123309-12-5 C₁₁H₁₄Br₂N₂O₂S 
• 708274-46-8 1,1-dimethylethyl (2S,4R)-4-amino-2-methyl-1-pyrrolidinecarboxylate 
• 1123305-81-6 tert-butyl (2S,4S)-2-methyl-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate 
• 924907-62-0 1,1-dimethylethyl (2R,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-{[(methylsulfonyl)oxy]methyl}-1-pyrrolidinecarboxylate 
• 1123305-82-7 1,1-dimethylethyl (2S,4R)-4-{[(2,5-dibromophenyl)sulfonyl]amino}-2-methyl-1-pyrrolidinecarboxylate 
• 708274-45-7 1,2-dimethylethyl-(2S,4R)-4-azido-2-methyl-1-pyrrolidinecarboxylate 
• 1123305-80-5 1,1-dimethylethyl (2S,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-methyl-1-pyrrolidinecarboxylate 
• 791602-89-6 4-(tert-butyldimethylsilanyloxy)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 

Relevant articles and documents

Discovery of novel cyanamide-based inhibitors of cathepsin C

The discovery of potent and selective cyanamide-based inhibitors of the cysteine protease cathepsin C is detailed. Optimization of the template with regard to plasma stability led to the identification of compound 17, a potent cathepsin C inhibitor with excellent selectivity over other cathepsins and potent in vivo activity in a cigarette smoke mouse model.