112343-23-4

Basic information

• Product Name: C₇₁H₈₀ClN₈O₁₄PSi₂
• CAS NO: 112343-23-4
• Molecular Weight: 1392.06
• Mol File: 112343-23-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₇₁H₈₀ClN₈O₁₄PSi₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₇₁H₈₀ClN₈O₁₄PSi₂(112343-23-4)
• EPA Substance Registry System: C₇₁H₈₀ClN₈O₁₄PSi₂(112343-23-4)

Safety Data

• Hazardous Substances Data: 112343-23-4(Hazardous Substances Data)

Upstream product

• 2338-12-7 5-nitrobenzotriazole 
• 69504-07-0 N⁶-benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine 
• 15074-54-1 2-chlorophenyl dichlorophosphate 
• 72409-30-4 N⁴-benzoyl-2'-O-(tert-butyldimethylsilyl)-5'-O-(4-monomethoxytrityl)cytidine 

Relevant articles and documents

Formation of Interribonucleoside Phosphate Bond by the Use of Reagent Formed by the Reaction of 2-Chlorophenyl Phosphorodichloridate with 5-Nitrobenzotriazole and Preparation of Anticodon Triplet of Yeast tRNALys

The reagent formed by the reaction of 2-chlorophenyl phosphorodichloridate with an equimolar amount of 5-nitrobenzotriazole was treated with protected ribonucleosides having free 3'-OH, followed by protected ribonucleosides having free 5'-OH in pyridine for 8 h (the second step), the corresponding dinucleoside phosphates being obtained in 55-84 percent yields.When the second step was carried out in the presence of 2,6-lutidine, the yields were increased to 80-90 percent within 2 h.By this procedure, the anticodon triplet of yeast tRNALys was prepared in 71 percent yield.