112343-44-9Relevant academic research and scientific papers
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein–Protein Interactions
Ali, Ameena M.,Atmaj, Jack,D?mling, Alexander,Groves, Matthew,Holak, Tad A.,Labuzek, Beata,Neochoritis, Constantinos G.,Plewka, Jacek,Ricardo, Manuel G.,Rivera, Daniel G.,Skalniak, Lukasz,Surmiak, Ewa,Zhang, Ran
, p. 5235 - 5241 (2020)
Stapled peptides are chemical entities in-between biologics and small molecules, which have proven to be the solution to high affinity protein–protein interaction antagonism, while keeping control over pharmacological performance such as stability and mem
Supramolecular compounds from multiple ugi multicomponent macrocyclizations: Peptoid-based cryptands, cages, and cryptophanes
Rivera, Daniel G.,Wessjohann, Ludger A.
, p. 7122 - 7123 (2007/10/03)
The first 3-fold multicomponent macrocyclizations of trifunctional building blocks were developed to produce, in one pot, cryptands, cages, and cryptophanes with peptoid tethers carrying additional recognition motifs. The straightforward, efficient, and d
