4973-73-3Relevant academic research and scientific papers
Room Temperature One-Step Conversion from Elemental Sulfur to Functional Polythioureas through Catalyst-Free Multicomponent Polymerizations
Tian, Tian,Hu, Rongrong,Tang, Ben Zhong
, p. 6156 - 6163 (2018)
The utilization of sulfur is a global concern, considering the abundant and cheap source of sulfur from nature and petroleum industry, its limited consumption, and the safety/environmental problems caused during storage. The economic and efficient transformation of sulfur remains to be a great challenge for both academia and industry. Herein, a room temperature conversion from sulfur to functional polythioureas was reported through a catalyst-free multicomponent polymerization of sulfur, aliphatic diamines, and diisocyanides in air with 100% atom economy. The polymerization enjoys quick reaction and wide monomer scope, which affords 16 polythioureas with well-defined structures, high molecular weights (Mws up to 242 500 g/mol), and excellent yields (up to 95%). The polythioureas can be utilized to detect mercury pollution with high sensitivity (Ksv = 224 900 L/mol) and high selectivity, clean Hg2+ with high removal efficiency (>99.99%) to achieve drinking water standard, and monitor the real-time removal process by fluorescence.
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein–Protein Interactions
Ali, Ameena M.,Atmaj, Jack,D?mling, Alexander,Groves, Matthew,Holak, Tad A.,Labuzek, Beata,Neochoritis, Constantinos G.,Plewka, Jacek,Ricardo, Manuel G.,Rivera, Daniel G.,Skalniak, Lukasz,Surmiak, Ewa,Zhang, Ran
supporting information, p. 5235 - 5241 (2020/02/15)
Stapled peptides are chemical entities in-between biologics and small molecules, which have proven to be the solution to high affinity protein–protein interaction antagonism, while keeping control over pharmacological performance such as stability and mem
Supramolecular compounds from multiple ugi multicomponent macrocyclizations: Peptoid-based cryptands, cages, and cryptophanes
Rivera, Daniel G.,Wessjohann, Ludger A.
, p. 7122 - 7123 (2007/10/03)
The first 3-fold multicomponent macrocyclizations of trifunctional building blocks were developed to produce, in one pot, cryptands, cages, and cryptophanes with peptoid tethers carrying additional recognition motifs. The straightforward, efficient, and d
