1123495-75-9Relevant academic research and scientific papers
Palladium-Catalyzed Decarbonylative Dehydration for the Synthesis of α-Vinyl Carbonyl Compounds and Total Synthesis of (-)-Aspewentins A, B, and C
Liu, Yiyang,Virgil, Scott C.,Grubbs, Robert H.,Stoltz, Brian M.
supporting information, p. 11800 - 11803 (2015/10/05)
The direct α-vinylation of carbonyl compounds to form a quaternary stereocenter is a challenging transformation. It was discovered that δ-oxocarboxylic acids can serve as masked vinyl compounds and be unveiled by palladium-catalyzed decarbonylative dehydr
Total syntheses of (-)- and (+)-goniomitine
Mizutani, Masaya,Inagaki, Fuyuhiko,Nakanishi, Takeo,Yanagihara, Chihiro,Tamai, Ikumi,Mukai, Chisato
supporting information; experimental part, p. 1796 - 1799 (2011/06/19)
The Stille coupling reaction of 3-(benzyloxymethyl)-1-(tert- butyldiphenylsiloxy)ethyl-1-(tributylstannyl)allene with N-(tert-butoxycarbonyl) -2-iodoaniline directly produced the corresponding 2-vinylindole derivative, which was independently transformed
Toward general access to the Aspidosperma-type terpenoid indole alkaloids: Synthesis of the key 3,3-disubstituted piperidones through enantioselective intramolecular Heck-type reaction of chloroformamides
Yasui, Yoshizumi,Takeda, Hiroshi,Takemoto, Yoshiji
experimental part, p. 1567 - 1574 (2009/11/30)
An enantioselective intramolecular Heck-type reaction of chloroformamides has been developed for the synthesis of 3,3-disubstituted piperidones. The desired piperidone was formed in the presence of a palladium catalyst, an optically active phosphoramidite ligand, K3PO4 and Ag 3PO4. The obtained piperidone was converted to epieburnamonine.
