1123546-35-9Relevant articles and documents
Novel fluorinated pseudopeptides as proteasome inhibitors
Formicola, Lucia,Marechal, Xavier,Basse, Nicolas,Bouvier-Durand, Michelle,Bonnet-Delpon, Daniele,Milcent, Thierry,Reboud-Ravaux, Michele,Ongeri, Sandrine
, p. 83 - 86 (2009)
We have designed novel small inhibitors of rabbit 20S proteasome using a trifluoromethyl-β-hydrazino acid scaffold. Structural variations influenced their inhibition of the three types of active sites. Proteasome inhibition at the micromolar level was sel