1123546-52-0Relevant academic research and scientific papers
Novel fluorinated pseudopeptides as proteasome inhibitors
Formicola, Lucia,Marechal, Xavier,Basse, Nicolas,Bouvier-Durand, Michelle,Bonnet-Delpon, Daniele,Milcent, Thierry,Reboud-Ravaux, Michele,Ongeri, Sandrine
supporting information; experimental part, p. 83 - 86 (2009/06/18)
We have designed novel small inhibitors of rabbit 20S proteasome using a trifluoromethyl-β-hydrazino acid scaffold. Structural variations influenced their inhibition of the three types of active sites. Proteasome inhibition at the micromolar level was sel
