1123786-75-3 Usage
Molecular Weight
190.24 g/mol
Structure
2-(3-phenyloxetan-3-yl)ethanol consists of an oxetane ring (a three-membered ring with one oxygen atom and two carbon atoms) with a phenyl group attached to the carbon atom of the ring, and an ethanol group attached to the carbon atom next to the oxetane ring.
Polarity
The presence of the phenyl group and the ethanol group makes the compound polar.
Solubility
2-(3-phenyloxetan-3-yl)ethanol is soluble in organic solvents such as ethanol, methanol, and acetone.
Boiling Point
The boiling point of 2-(3-phenyloxetan-3-yl)ethanol is not readily available, but it is expected to have a high boiling point due to the presence of the phenyl group and the ethanol group.
Uses
2-(3-phenyloxetan-3-yl)ethanol is primarily used in organic synthesis and as a building block for the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. It is also used as an intermediate in the production of a wide range of organic compounds with diverse applications.
Potential Applications
2-(3-phenyloxetan-3-yl)ethanol may have potential applications in the field of medicinal chemistry and drug development due to its structural features.
Check Digit Verification of cas no
The CAS Registry Mumber 1123786-75-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,3,7,8 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1123786-75:
(9*1)+(8*1)+(7*2)+(6*3)+(5*7)+(4*8)+(3*6)+(2*7)+(1*5)=153
153 % 10 = 3
So 1123786-75-3 is a valid CAS Registry Number.
1123786-75-3Relevant articles and documents
Asymmetric Desymmetrization of Oxetanes for the Synthesis of Chiral Tetrahydrothiophenes and Tetrahydroselenophenes
Zhang, Renwei,Guo, Wengang,Duan, Meng,Houk,Sun, Jianwei
, p. 18055 - 18060 (2019/11/13)
Chiral tetrahydrothiophenes and tetrahydroselenophenes are highly useful structural units. Described here is a new catalytic asymmetric approach for their synthesis. With a suitable chiral Br?nsted acid catalyst, an oxetane desymmetrization by a well-positioned internal sulfur or selenium nucleophile proceeded efficiently to generate all-carbon quaternary stereocenters with excellent enantioselectivities. Taming the sulfur and selenium nucleophile in the form of a thioester and selenoester, respectively, is crucial to the success of this work. This approach also allows the facile synthesis of chiral tetrahydrothiopyrans. Mechanistic studies, including DFT calculations, suggested an intramolecular acyl-transfer pathway. Utilities of the chiral products are also demonstrated.
