1123797-70-5Relevant academic research and scientific papers
Imidazole-mediated cascade [2 + 2 + 2] annulation reactions: A highly diastereoselective synthetic protocol for the construction of multiply substituted cyclohexanes
Liu, Xu-Guang,Shi, Min
, p. 6168 - 6174 (2008)
A novel imidazole-mediated [2 + 2 + 2] annulation process that enables the diastereoselective synthesis of multiply substituted cyclohexanes 3 in a one-pot, three-component manner from two units of (arylmethylidene) malononitriles 1 and one unit of nitroalkenes 2 is described. These cyclohexane derivatives were obtained in moderate to good yields under mild conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
