27675-37-2

Basic information

• Product Name: 1-NITROBUT-1-ENE
• Synonyms: 1-NITROBUT-1-ENE
• CAS NO: 27675-37-2
• Molecular Formula: C₄H₇NO₂
• Molecular Weight: 101.1039
• Mol File: 27675-37-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 147.2°Cat760mmHg
• Flash Point: 47.2°C
• Appearance: /
• Density: 1.001g/cm³
• Vapor Pressure: 5.66mmHg at 25°C
• Refractive Index: 1.441
• CAS DataBase Reference: 1-NITROBUT-1-ENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-NITROBUT-1-ENE(27675-37-2)
• EPA Substance Registry System: 1-NITROBUT-1-ENE(27675-37-2)

Safety Data

• Hazardous Substances Data: 27675-37-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H7NO2/c1-2-3-4-5(6)7/h3-4H,2H2,1H3/b4-3+

Upstream product

• 3156-74-9 1-nitro-2-butanol 
• 57988-25-7 2-chloro-1-nitro-butane 
• 127-08-2 potassium acetate 
• 3156-75-0 acetic acid-(1-nitromethyl-propyl ester) 
• 127-09-3 sodium acetate 
• 75-52-5 nitromethane 
• 123-38-6 propionaldehyde 
• 60-29-7 diethyl ether 
• 89181-98-6 1,1,1-trinitro-2-nitromethyl-butane 
• 106-98-9 1-butylene 
• 75-09-2 dichloromethane 

Downstream Products

• 53607-75-3 1-Chlor-2-methoxy-1-nitro-butan 
• 185426-02-2 (1S,2R,1'R)-(-)-N-<1-methyl-2-(1'-nitromethylpropoxy)-2-phenylethyl>formamide 
• 412021-15-9 (1R,2R)-2-Nitromethyl-1-phenyl-butane-1-sulfonic acid (3aR,5R,6R,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 412021-30-8 (1R,2R)-1-(4-tert-Butyl-phenyl)-2-nitromethyl-butane-1-sulfonic acid (3aR,5R,6R,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 873990-75-1 N-(1-nitrobutan-2-yl)benzenamine 
• 1312081-81-4 (S,E)-4-(nitromethyl)-1-phenylhex-1-en-3-one 
• 1123200-89-4 C₁₈H₂₀N₂O₃ 
• 1123200-80-5 C₁₇H₁₈N₂O₃ 
• 1123200-90-7 C₁₇H₁₇FN₂O₃ 

Relevant articles and documents

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Reaction behaviour of arylamines with nitroalkenes in the presence of bismuth(iii) triflate: An easy access to 2,3-dialkylquinolines

We report the reaction behaviour of arylamines with nitroalkenes in the presence of bismuth(iii) triflate (10 mol%) and diacetoxyiodobenzene (10 mol%). We obtained 2,3-dialkylquinoline derivatives instead of the expected 3-alkylindole derivatives. The present reaction is an alternative approach for the synthesis of 2,3-dialkylquinoline derivatives under milder conditions. Furthermore, we establish the mechanistic pathway by theoretical calculations using Gaussian 09 software [B3LYP/6-311+G(d,p)], which shows that the conventional aza-Michael reaction is preferred over Michael addition. Aliphatic nitroalkenes behave in a different manner than aromatic nitroalkenes. An aza-Michael adduct gives rise to an imine by the elimination of water which may tautomerize to the corresponding enamine. The resulting imine and enamine intermediates react together to afford the desired quinoline derivatives. This protocol has the advantages of consecutive formation of one C-N and two C-C bonds, high regioselectivity, broad substrate-scope and good yields.

Highly Enantioselective Michael Addition of Dithiomalonates to Nitroolefins Catalyzed by New Bifunctional Chiral Thioureas

We report a highly efficient asymmetric Michael addition of dithiomalonates to trans -β-nitroole?ns catalyzed by versatile cinchona-based bifunctional thioureas, which provides the corresponding adducts in high yields (up to 92%) and with excellent enanti