1123816-53-4

Upstream product

• 843638-10-8 2-amino-7-(4-methoxyphenyl)-5-phenyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidine 
• 98-88-4 benzoyl chloride 

Relevant academic research and scientific papers

2-Amino-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidines: Synthesis and reactions with electrophilic reagents

The hydrogenation of 2-amino-5-R-7-R′-4,7-dihydro-1,2,4-triazolo[1,5- a]pyrimidines with NaBH4 led to the formation of 2-amino-5-R-7- R′-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidines. Acylation, sulfonylation, and alkylation of these compounds depending on conditions and the reagent character occur at the amino group, atoms N3 or N 4. The treatment with alkali of 2-amino-3-benzyl-5-R-7-R′-4,5, 6,7-tetrahydro-1,2,4-triazolo-[1,5-a]pyrimidinium bromide resulted in 2-amino-3-benzyl-5-R-7-R′-3,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a] -pyrimidine, similar reaction of 2-acetamido-3-benzyl-5-R-7-R′-4,5,6,7- tetrahydro-1,2,4-triazolo[1,5-a]-pyrimidinium bromide gave a mesoionic product of a hydrogen elimination from the amide nitrogen atom.