1123850-99-6Relevant articles and documents
A Novel Method for the In Situ Generation of Alkoxydialkylboranes and Their Use in the Selective Preparation of 1,3-Syn Diols
Chen, Kau-Ming,Gunderson, Karl G.,Hardtmann, Goetz E.,Prasad, Kapa,Repic, Oljan,Shapiro, Michael J.
, p. 1923 - 1926 (1987)
An in situ method for generating Et2BOCH3 from triethylborane and methanol without using any other catalysts is described.Using the Et2BOCH3 thus generated as a chelating agent, syn 1,3-diols are prepared in > 98 percent stereochemical purity by reducing β-hydroxy-ketones with sodium borohydride
A convenient stereoselective synthesis of 5-hydroxy-3-oxoesters and 3-hydroxy-5-oxoesters
??d?o-Dobrowolska, Anna,Schrittwieser, Joerg H.,Grischek, Barbara,Koszelewski, Dominik,Kroutil, Wolfgang,Ostaszewski, Ryszard
, p. 797 - 802 (2017/06/13)
A biocatalytic approach was employed for the asymmetric reduction of sterically demanding ketones to prepare 3-hydroxy-5-oxo-5-phenylpentanoates and 5-hydroxy-3-oxo-5-phenylpentanoates. Screening a collection of microorganisms led to the identification of
A concise total synthesis of diospongins A and B
Sabitha, Gowravaram,Padmaja, Pannala,Yadav, Jhillu S.
experimental part, p. 2235 - 2239 (2009/03/12)
The total synthesis of the diarylheptanoids (-)-diospongin A (1) and B (2) was achieved stereoselectively via the δ-lactone intermediate 6. The key reactions involved are a stereoselective reduction of β-keto ester and the Horner-Wadsworth-Emmons and intramolecular oxy-Michael reactions.
