1123858-30-9Relevant academic research and scientific papers
A green approach for efficient synthesis of N-substituted pyrroles in ionic liquid under microwave irradiation
Meshram,Prasad,Aravind Kumar
, p. 3477 - 3480 (2010)
A rapid synthesis of N-substituted pyrroles has been described by the reaction of 4-hydroxyproline with isatins in ionic liquid under microwave irradiation. The recovered ionic liquid was reused for six cycles. The reaction proceeds without the addition o
Novel aqueous phase supramolecular synthesis of 3-pyrrolyl-indolin-2-ones and pyrrolylindeno[1,2-b]quinoxalines
Sridhar,Srinivas,Pavan Kumar,Prakash Reddy,Vijay Kumar,Rama Rao
, p. 1489 - 1492 (2008)
Various 3-pyrrolylindolin-2-ones and pyrrolylindeno[1,2-b]quinoxaline were synthesized for the first time in high yields in water under neutral conditions by supramolecular catalysis involving β-cyclodextrin. The β-cyclodextrin can be recovered and reused a number of times without any loss of activity.
3-Pyrrolyl-oxindoles as efficient nucleophiles for organocatalytic asymmetric synthesis of structurally diverse 3,3′-disubstituted oxindole derivatives
Cui, Bao-Dong,You, Yong,Zhao, Jian-Qiang,Zuo, Jian,Wu, Zhi-Jun,Xu, Xiao-Ying,Zhang, Xiao-Mei,Yuan, Wei-Cheng
, p. 757 - 760 (2015)
A range of 3-pyrrolyl-3,3′-disubstituted oxindoles were smoothly obtained via the reaction of 3-pyrrolyl-oxindoles with nitroalkenes using an organocatalyst. The usefulness of the protocol was also demonstrated by the versatile conversions of the Michael adducts into other functionalized 3,3′-disubstituted oxindoles, as well as into the analogues of some valuable natural products.
Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles
Ni, Qijian,Wang, Xuyang,Zeng, Da,Wu, Qianling,Song, Xiaoxiao
supporting information, p. 2273 - 2278 (2021/04/05)
An asymmetric [3+3] cyclization of nitroenynes and 3-pyrrolyloxindoles has been realized with a chiral bifunctional squaramide catalyst. This Michael/Friedel-Crafts cascade strategy provides a facile and efficient access to enantioenriched polycyclic aza-spirooxindoles with 32-95% isolated yields and excellent stereocontrol under mild reaction conditions.
