112393-80-3Relevant academic research and scientific papers
Inhibition of 5-lipoxygenase by substituted 3,4-dihydro-2H-1,4-thiazines
Weintraub,Skoog,Nichols,Wiseman,Huber,Baugh,Farrell
, p. 937 - 943 (2007/10/02)
A series of substituted 3,4-dihydro-2H-1,4-thiazines inhibit 5-lipoxygenase from rat leukocytes and exhibit submicromolar IC50 values. A novel synthesis of these compounds was developed based on the formation of hydroxymethyleneamine 13 and its
HETEROCYCLES. 11. SULFUR ANALOGS OF 3-(3-HYDROXYPHENYL)-N-n-PROPYLPIPERIDINE
Weintraub, Philip M.,Miller, Frank P.,Wiech, Norbert L.
, p. 1503 - 1516 (2007/10/02)
Analogs of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) and 3-(3-hydroxyphenyl)-N-(2-phenylethyl)piperidine (phenethyl 3-PP) in which carbon 4 was replaced by sulfur were synthesized and tested for dopamine autoreceptor activity.
