88788-99-2

Upstream product

• 86215-57-8 bromo-(3-methoxy-phenyl)-acetic acid methyl ester 
• 18927-05-4 methyl (3-methoxyphenyl)acetate 
• 112393-96-1 2-(3-methoxyphenyl)-4-propyl-3-thiomorpholinone 
• 112393-99-4 methyl <2-<<<(3-methylphenyl)methyl>thio>ethyl>propyl>carbamate 
• 112394-04-4 N-<2-<<(3-methoxyphenyl)methyl>thio>ethyl>propanamide 
• 112393-93-8 2-(3-methoxyphenyl)-4-propylthiomorpholine 
• 112394-02-2 N-<2-<<(3-methoxyphenyl)methyl>thio>ethyl>-1-propanamine 
• 824-98-6 m-methoxybenzyl chloride 
• 112393-79-0 2,2,2-trichloroethyl 2-(3-methoxyphenyl)-4-thiomorpholinecarboxylate 

Downstream Products

• 112393-80-3 3,4,5,6-tetrahydro-6-(3-methoxyphenyl)-4-(2-phenylethyl)-2H-1,4-thiazine 
• 1598382-96-7 2-(3-methoxyphenyl)-1,1-dioxo-1λ⁶-thiomorpholine-4-carboxylic acid tert-butyl ester 
• 1369007-67-9 2-(3-methoxyphenyl)thiomorpholine1,1-dioxide 
• 1598382-97-8 (S)-1,1,1-trifluoro-3-[2-(3-methoxyphenyl)-1,1-dioxo-1λ⁶-thiomorpholin-4-yl]-propan-2-ol 
• 1598382-27-4 (4-chlorophenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-2-(3-methoxyphenyl)-1,1-dioxo-1λ⁶-thiomorpholin-4-ylmethyl]-ethyl ester 
• 1598382-95-6 tert-butyl 2-(3-methoxyphenyl)thiomorpholine-4-carboxylate 

Relevant academic research and scientific papers

SUBSTITUTED PHENYLCARBAMATE COMPOUNDS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.

HETEROCYCLES. 11. SULFUR ANALOGS OF 3-(3-HYDROXYPHENYL)-N-n-PROPYLPIPERIDINE

Analogs of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) and 3-(3-hydroxyphenyl)-N-(2-phenylethyl)piperidine (phenethyl 3-PP) in which carbon 4 was replaced by sulfur were synthesized and tested for dopamine autoreceptor activity.