112402-71-8Relevant academic research and scientific papers
Synthesis and antimalarial activity of some triphenyltin(IV) aminobenzoate compounds against Plasmodium falciparum
Fenska, Mona Dwi,Hadi, Sutopo,Naseer, Muhammad Moazzam,Noviany, Noviany,Satria, Heri,Simanjuntak, Wasinton
, p. 256 - 260 (2021/10/29)
This paper presents antimalarial activity of several triphenyltin(IV) aminobenzoate compounds synthesized from the reaction of triphenyltin(IV) hydroxide with 2-, 3-, and 4-aminobenzoic acid. The activity of the compounds as anti-malaria agents was evaluated using Plasmodium falciparum, and demonstrated that the compounds have about the same IC50 with that of chloroquine (2×10-3 μg/mL) applied as the positive control. The result also showed that the Plasmodium is non-resistent to the compounds synthesized, which is the opposite to chloroquine.
Triorganotin(IV) Benzoates and Aminobenzoates
Sandhu, G. K.,Verma, S. P.,Moore, L. S.,Parish, R. V.
, p. 15 - 26 (2007/10/02)
Complexes of the general formula R3SnX, where X is the anion of benzoic acid, o-, m-, p-amino- or N-phenyl-o-amino-benzoic acid, have been prepared and characterised.A combination of molecular weight, infrared, 1H NMR and 119Sn Moessbauer measurements show that, the amino-nitrogen atoms are not coordinated to tin.When R= phenyl or cyclohexyl, the compounds are monomeric and four-coordinate, and when R is alkyl (Me, n-Pr, n-Bu) they are monomeric and five-coordinate, with a bidentate carboxylate in the equatorial position of a trigonal bipyramidal structure.
