112403-98-2

Basic information

• Product Name: N-methoxy-2-(4-methoxyphenyl)acetamide
• CAS NO: 112403-98-2
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.2151
• Mol File: 112403-98-2.mol
• Article Data: 7

Chemical Properties

• Density: 1.115g/cm³
• Refractive Index: 1.511
• CAS DataBase Reference: N-methoxy-2-(4-methoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methoxy-2-(4-methoxyphenyl)acetamide(112403-98-2)
• EPA Substance Registry System: N-methoxy-2-(4-methoxyphenyl)acetamide(112403-98-2)

Safety Data

• Hazardous Substances Data: 112403-98-2(Hazardous Substances Data)

Upstream product

• 67-62-9 O-Methylhydroxylamin 
• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 593-56-6 N-methoxylamine hydrochloride 
• 104-01-8 4-Methoxyphenylacetic acid 
• 112404-05-4 potassium (p-methoxyphenyl)acetohydroxamate 
• 74-88-4 methyl iodide 

Downstream Products

• 128917-49-7 2-(4-hydroxyphenyl)-N-methoxyacetamide 
• 137042-70-7 C₁₀H₁₂BrNO₂ 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 104-47-2 p-methoxybenzylnitrile 

Relevant articles and documents

Photoinduced Aerobic Iodoarene-Catalyzed Spirocyclization of N-Oxy-amides to N-Fused Spirolactams**

Iodoarene catalysis is a powerful methodology that usually requires an excess of oxidant, or of redox mediator if the terminal oxidant is dioxygen, to generate the key hypervalent iodine intermediate to proceed efficiently. We report that, using the spiro-cyclization of amides as a benchmark reaction, aerobic iodoarene catalysis can be enabled by relying on a pyrylium photocatalyst under blue light irradiation. This unprecedented dual organocatalytic system allows the use of low catalytic loading of both catalysts under very mild operating conditions.

Spirolactams and their synthesis

New spirolactams having a benzodienone moiety and a azetidinone moiety which are highly stable due to pi interactions. They are useful as UV absorbers and as synthetic intermediates.

A new synthesis of nitriles from N-alkoxyimidoyl halides with zinc

Both aliphatic and aromatic nitriles are obtained from the corresponding N-methoxy-, N-benzyloxy- or N-tert-butoxyimidoyl halides with zinc in a acetic acid/dimethylformamide mixture (1:1).