112405-69-3

Upstream product

• 100-46-9 benzylamine 
• 112405-76-2 1-Benzyl-3-chloro-4-methyl-3-(1-trimethylsilanyl-vinyl)-azetidin-2-one 
• 112405-73-9 1-Benzyl-4-methyl-3-[1-trimethylsilanyl-eth-(E)-ylidene]-azetidin-2-one 
• 112405-62-6 1-Benzyl-4-methyl-3-vinylidene-azetidin-2-one 
• 100-39-0 benzyl bromide 
• 115869-86-8 (3R,4S)-1-Benzyl-3-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-azetidin-2-one 

Downstream Products

• 115869-90-4 N-((2R,3S)-1-Benzyl-2-methyl-4-oxo-azetidin-3-yl)-acetamide 
• 115869-90-4 N-((2R,3R)-1-Benzyl-2-methyl-4-oxo-azetidin-3-yl)-acetamide 
• 115869-88-0 1-Benzyl-4-methyl-azetidine-2,3-dione 3-oxime 

Relevant academic research and scientific papers

A NOVEL SYNTHETIC METHOD OF LACTAMS FROM 1,3-DIOXIN-4-ONES VIA INTRAMOLECULAR KETENE TRAPPING

A novel route to four- and five-membered lactams from 1,3-dioxin-4-ones having an α-aminoalkyl side-chain at 5- or 6-position through cycloreversion to acylketenes followed by intramolecular ketene trapping by the amino function is described.

A NITRONE-BASED APPROACH TO THE SYNTHESIS OF CIS-3-AMIDO AZETIDINONES

The utilization of a nitrosation reaction in concert with a nitrone-based approach to the synthesis of important 3-oximino β-lactams, 7a, b, c is described.