112433-51-9Relevant articles and documents
1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE
-
Page/Page column 34, (2010/11/27)
The present invention relates to a compound represented by Formula (I): wherein Ar1, Ar2, R1 and R2 each represent a substituent, a salt thereof, or a solvate of the compound or the salt, and to a medicine containing the same. According to the present invention, a potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.
Improved syntheses of fluorinated tertiary butylamines
Ok, Dong,Fisher, Michael H.,Wyvratt, Matthew J.,Meinke, Peter T.
, p. 3831 - 3834 (2007/10/03)
Two new and efficient methods using cyclic sulfamidate and nitrone chemistry were developed for the synthesis of the sterically congested 1,1- dimethyl-2-fluoroethylamine (1), 2-fluoro-1-(fluoromethyl)-1-methylethylamine (2) and 2-fluoro-1,1-bis-(fluoromethyl)-ethylamine (3).
Fluorinated tertiary butylamines
-
, (2008/06/13)
New fluorinated tertiary butylamines of the formula STR1 are prepared from halogenated pivalic acid halides by a reaction sequence which comprises preparing the fluorinated pivalic acid and decomposition of the azide to the corresponding isocyanate. The isocyanate can be converted to the fluorinated tertiary butylamine acid addition salt by acid hydrolysis or directly to the amine by treatment with base. In addition, the present amines can be prepared by reaction of a pivalic acid amide with hypochlorite. The new butylamines can be used in the preparation of benzoic acid amides having insecticidal action.