112435-23-1Relevant academic research and scientific papers
A SHORT STEP SYNTHESIS OF CLAVICIPITIC ACIDS FROM 4-CYANOMETHYLINDOLE
Matsumoto, Masakatsu,Kobayashi, Hisako,Watanabe, Nobuko
, p. 1197 - 1202 (2007/10/02)
4-(3-methyl-1-oxo-2-buten-1-yl)indole (3) was efficiently synthesized from 4-cyanomethyl-1-(p-toluenesulfonyl)indole by alkylation with 2-methyl-2-buten-1-yl tosylate and by successive aerobic oxidation and deprotection of N-tosyl group.The acylindole 3 was used for a short step synthesis of clavicipitic acids (4).
