71516-40-0

Upstream product

• 76989-06-5 5-bromo-4-oxo-N-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole 
• 92573-20-1 [1-(Toluene-4-sulfonyl)-1,5,6,7-tetrahydro-indol-(4E)-ylidene]-acetonitrile 

Downstream Products

• 155591-00-7 1-(p-toluenesulfonyl)indol-4-acetic acid 
• 33062-26-9 (+/-)-4,6-cis-clavicipitic acid 
• 33062-26-9 (+/-)-4,6-trans-clavicipitic acid 
• 112435-23-1 3-Methyl-1-[1-(toluene-4-sulfonyl)-1H-indol-4-yl]-but-2-en-1-one 
• 112435-22-0 3-Methyl-1-[1-(toluene-4-sulfonyl)-1H-indol-4-yl]-but-3-en-1-one 

Relevant academic research and scientific papers

A FACILE SYNTHESIS OF 4-(CYANOMETHYL)INDOLES AND 4-(ETHOXYCARBONYL-METHYL)INDOLES FROM 5-HALO-4-OXO-4,5,6,7-TETRAHYDROINDOLES

4-(Cyanomethyl)indoles and 4-(ethoxycarbonylmethyl)-indoles were synthesized from 5-halo-4-oxo-4,5,6,7-tetrahydroindoles by means of Horner-Wittig reaction and succesive dehydrohalogenation.

SYNTHESIS OF 4-( CYANOMETHYLIDENE)- AND 4-( ETHOXYCARBONYLMETHYLIDENE)-4,5,6,7-TETRAHYDROINDOLES AND THEIR DEHYDROGENATION TO 4-( CYANOMETHYL)- AND 4-( ETHOXYCARBONYLMETHYL)INDOLES

The Horner-Wittig reaction of 4-oxo-4,5,6,7-tetrahydroindoles with (EtO)2P(O)CH2CN and (EtO)2P(O)CH2CO2Et yielded respectively 4-(cyanomethylidene)- and 4-(ethoxycarbonylmethylidene)-4,5,6,7-tetrahydroindoles, which were catalytically dehydrogenated to 4-