112439-12-0

Upstream product

• 112438-96-7 Toluene-4-sulfonic acid 1-diphenoxymethyl-2,2-dimethyl-propyl ester 
• 112438-57-0 3,3-Dimethyl-1,1-diphenoxy-butan-2-one 
• 112438-75-2 3,3-Dimethyl-1,1-diphenoxy-butan-2-ol 
• 99586-98-8 1,1-dibromo-3,3-dimethyl-1-butene 
• 108-95-2 phenol 

Downstream Products

• 112439-15-3 1-((E)-3,3-Dimethyl-1-phenoxy-but-1-enyl)-1H-[1,2,4]triazole 

Relevant academic research and scientific papers

Copper-catalyzed coupling of 1,1-dibromo-1-alkenes with phenols: A general, modular, and efficient synthesis of ynol ethers, bromo enol ethers, and ketene acetals

An efficient and general copper-catalyzed method is reported for the synthesis of phenol-derived 1-bromoenol ethers, ynol ethers, and ketene acetals by chemodivergent copper-catalyzed cross-coupling between readily available 1,1-dibromo-1-alkenes and phen

Copper-mediated selective cross-coupling of 1,1-dibromo-1-alkenes and heteronucleophiles: Development of general routes to heterosubstituted alkynes and alkenes

Efficient and general procedures for the cross-coupling of 1,1-dibromoalkenes and N-, O-, and P-nucleophiles are reported. Fine-tuning of the reaction conditions allows for either site-selective, double, or alkynylative cross-coupling, therefore providing

A Facile Synthesis of Ketene O,N-Acetals and Ketene O,O-Acetals by Tosylate Elimination

Reaction of the alcohols 4 and 5 with p-toluensulfonyl chloride leads to the sulfonic esters 6 and 7, respectively, which on treatment with potassium tert-butylate easily react to give the ketene O,N-acetals 8 and O,O-acetals 9, respectively.The (E/Z) isomers 8 arising from the elimination reaction of 7 were identified by their 1H-NMR data after X-ray analysis of one of the isomers of 8e.On one example it is shown that the elimination reaction proceeds stereoselectively "anti".