112463-04-4

Upstream product

• 108-24-7 acetic anhydride 
• 112463-02-2 (+)-5-hydroxysedamine 
• 165674-77-1 Methyl (2R,5S)-5-(tert-butyldimethylsilyloxy)-2-(2-oxo-2-phenylethyl)piperidine-1-carboxylate 
• 165674-71-5 Methyl (2R,5R,2'R)-5-hydroxy-2-(2-hydroxy-2-phenylethyl)piperidine-1-carboxylate 
• 165674-78-2 Methyl (2R,5S)-5-hydroxy-2-(2-oxo-2-phenylethyl)piperidine-1-carboxylate 
• 165674-69-1 Methyl (2R,5S)-5-(mesyloxy)-2-(2-oxo-2-phenylethyl)piperidine-1-carboxylate 
• 165674-70-4 Methyl (2R,5R)-5-acetoxy-2-(2-oxo-2-phenylethyl)piperidine-1-carboxylate 
• 138565-92-1 methyl (2RS,5S)-5-(tert-butyldimethylsilyloxy)-2-ethoxypiperidine-1-carboxylate 

Relevant academic research and scientific papers

Synthesis of (+)- and (-)-Hydroxysedamine and (+)-N-Methylpseudoconhydrine from (S)-Glutamic Acid via Homochiral Acyliminium Ion

Efficient syntheses of (+)-N-methylpseudoconhydrine (5) and (-)-hydroxysedamine (10) are described starting from the readily available (2RS,5S)-Methyl 5-(tert-butyldimethylsilyloxy)-2-ethoxypiperidine-1-carboxylate (1) and proceeding via homochiral acylim