1125-30-0 Usage
General Description
1,3,5-Trimethyl-4-nitro-1H-pyrazole, also known as Pirodustat, is a chemical compound that belongs to the class of pyrazoles. It is a potent inhibitor of the enzyme prolyl hydroxylase, which is involved in the regulation of erythropoietin, a hormone that stimulates red blood cell production. Pirodustat is currently being studied as a potential treatment for anemia associated with chronic kidney disease and has shown promising results in early clinical trials. Additionally, Pirodustat has potential applications in the treatment of other diseases related to hypoxia and tissue ischemia, making it an important compound in the field of pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 1125-30-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1125-30:
(6*1)+(5*1)+(4*2)+(3*5)+(2*3)+(1*0)=40
40 % 10 = 0
So 1125-30-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H9N3O2/c1-4-6(9(10)11)5(2)8(3)7-4/h1-3H3
1125-30-0Relevant articles and documents
Reactions of pyrazoles and pyrazolium salts with complex metal hydrides and organometallic reagents. Synthesis of pyrazolines and pyrazolidines
Cuadrado, Purificacion,Gonzalez-Nogal, Ana M.,Martinez, Senen
, p. 8585 - 8598 (2007/10/03)
2-Pyrazolin-4-oximes have been synthesized by reaction of 4-nitroso- and 4-nitropyrazoles with complex metal hydrides and organometallic reagents. Furthermore, 4-nitropyrazolium tetrafluoroborates are reactive substrates towards organolithium and Grignard
