1125-73-1Relevant articles and documents
Process for the production of o-(N-monosubstituted amino)benzyl alcohols
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, (2008/06/13)
Process for the production of o-(N-monosubstituted amino)benzyl alcohols which comprises reacting an N-mono-substituted aniline optionally having one or more substituents with a boron trihalogenide at a temperature from about 0° C. to about 100° C. and reacting the resultant boron compound with an aldehyde in the presence of a base at a temperature from about -30° C. to about 100° C. to regiospecifically introduce a 1-hydroxy-alkyl or 1-hydroxy-substituted alkyl group into the ortho position of said aniline.