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7-Chloropteridine is a chemical compound belonging to the pteridine family, which are heterocyclic organic molecules with a pyrazino-pyrimidine core structure. This specific compound features a chlorine atom attached at the 7th position of the pteridine ring. 7-Chloropteridine is an important intermediate in the synthesis of various biologically active compounds, such as antifolates and antiprotozoal agents, due to its ability to inhibit dihydrofolate reductase, a key enzyme in the synthesis of DNA and RNA. It is also used as a building block in the development of new drugs targeting various diseases, including cancer and parasitic infections. The compound is typically synthesized through chemical reactions involving pteridine derivatives and is characterized by its chemical properties, such as solubility and stability, which are crucial for its applications in pharmaceutical research and development.

1125-84-4

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1125-84-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1125-84-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1125-84:
(6*1)+(5*1)+(4*2)+(3*5)+(2*8)+(1*4)=54
54 % 10 = 4
So 1125-84-4 is a valid CAS Registry Number.

1125-84-4Relevant academic research and scientific papers

Evaluation of electrophilic heteroaromatic substitution: Synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization

Wong, Fung Fuh,Huang, Yu-Ying,Chang, Chun-Hsi

, p. 8492 - 8500 (2012/11/07)

A new sequential three-component heterocyclization was developed by reacting aromatic and heterocyclic substrates, including aminobenzenes, 1-aminonaphthalene, 2-aminopyrazines, 5-aminopyrazoles, 3-aminopyridine, 5-aminopyrimidine, 5-aminoquinoline, and 8

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