2432-27-1

Basic information

• Product Name: 7(1H)-Pteridinone (9CI)
• Synonyms: 7(1H)-Pteridinone (9CI);7(8H)-Pteridinone;Pteridine-7(1H)-one
• CAS NO: 2432-27-1
• Molecular Formula: C6H4N4O
• Molecular Weight: 148.12216
• Product Categories: PYRIMIDINE
• Mol File: 2432-27-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 230 °C (decomp)(Solv: water (7732-18-5))
• Boiling Point: 268.68°C (rough estimate)
• Appearance: /
• Density: 1.4122 (rough estimate)
• Refractive Index: 1.6900 (estimate)
• PKA: 8.20±0.20(Predicted)
• Water Solubility: 1.11g/L(20 oC)
• CAS DataBase Reference: 7(1H)-Pteridinone (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 7(1H)-Pteridinone (9CI)(2432-27-1)
• EPA Substance Registry System: 7(1H)-Pteridinone (9CI)(2432-27-1)

Safety Data

• Hazardous Substances Data: 2432-27-1(Hazardous Substances Data)

Upstream product

• 13754-19-3 4,5-pyrimidinediamine 
• 49653-17-0 ethyl 2-ethoxyglycolate 
• 7732-18-5 water 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 

Downstream Products

• 2432-26-0 5H-pteridin-6-one 
• 102170-04-7 8-methyl-5,8-dihydro-pteridine-6,7-dione 
• 99584-31-3 7,8-Dihydro-6,8-dimethyl-7-oxo-pteridin 
• 857397-46-7 N-pteridin-7-yl-acetamide 
• 204443-30-1 7-Methylmercapto-pteridin 
• 769-66-4 7-Amino-pteridin 
• 81451-15-2 8H-pteridine-7-thione 
• 1125-84-4 7-chloropteridine 

Relevant articles and documents

Study on the isolation and chemical investigation of potential impurities in dexrazoxane using 2D-NMR and LC-PDA-MS

A chemical investigation of process related impurities associated with the synthesis of dexrazoxane was performed. The degradation product of dexrazoxane is known in the literature; however, the information related to process impurities is not available. For the first time, two process related impurities were isolated, characterized, and confirmed by their individual chemical synthesis. The present study describes the isolation methods of the impurities and their structural elucidation using IR, 1H, 13C, 2D NMR, and mass spectrometry. The identification of these impurities would be highly valuable for the quality control during the production of the dexrazoxane drug substance.