1125824-45-4Relevant academic research and scientific papers
Elucidating absolute configuration of unsaturated alcohols via enantioselective acylation reactions
Legay, Christina M.,Boudreau, Colton G.,Derksen, Darren J.
, p. 3432 - 3435 (2013/06/26)
Enantioselective nucleophilic acylation catalysis provides a simple method of determining absolute configuration for unsaturated alcohols. Extension of this technique to natural products and synthetic compounds, as well as current limitations of this appr
Synthesis of (-)-lobeline via enzymatic desymmetrization of lobelanidine
Chenevert, Robert,Morin, Pierre
experimental part, p. 1837 - 1839 (2009/05/26)
The bioactive alkaloid (-)-lobeline was synthesized via the stereoselective acylation (desymmetrization) of meso-lobelanidine by vinyl acetate in the presence of Candida antarctica lipase B.
Indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline: Application to the synthesis of (-)-sedamine
Zheng, Guangrong,Dwoskin, Linda P.,Crooks, Peter A.
, p. 8514 - 8517 (2007/10/03)
Alkyl chloroformates induced indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline is described. This strategy was applied to the conversion of (-)-lobeline to (-)-sedamine in high overall yield.
