[(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate]

Base Information

• Chemical Name: [(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate]
• CAS No.: 1125824-45-4
• Molecular Formula: C₂₄H₂₉NO₃
• Molecular Weight: 379.499
• Mol file: 1125824-45-4.mol

Synonyms:[(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate]

Chemical Property of [(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate]

There total 2 articles about [(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

lobelanidine monoacetate (1146626-22-3) → [(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate] (1125824-45-4)

Guidance literature:

With Jones reagent; In acetone; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2009.01.055

Reference yield:

acetic anhydride (108-24-7) + lobeline (90-69-7) → [(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate] (1125824-45-4)

Guidance literature:

With sodium acetate; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jo048848j

Reference yield:

[(S)-2-[(2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl]-1-phenylethyl acetate] (1125824-45-4) → lobeline (90-69-7)

Guidance literature:

With hydrogenchloride; water; In methanol; Reflux;

DOI:10.1016/j.bmc.2009.01.055

upstream raw materials:

acetic anhydride

lobeline

lobelanidine monoacetate

Downstream raw materials:

lobeline