1126-47-2

Basic information

• Product Name: 1,2-dithiolane-3,5-dicarboxylic acid (non-preferred name)
• Synonyms: 1,2-Dithiolane-3,5-dicarboxylic acid (non-preferred name)
• CAS NO: 1126-47-2
• Molecular Formula: C₅H₆O₄S₂
• Molecular Weight: 194.2287
• Mol File: 1126-47-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 421.2°C at 760 mmHg
• Flash Point: 208.6°C
• Density: 1.731g/cm³
• Vapor Pressure: 2.82E-08mmHg at 25°C
• Refractive Index: 1.679
• CAS DataBase Reference: 1,2-dithiolane-3,5-dicarboxylic acid (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dithiolane-3,5-dicarboxylic acid (non-preferred name)(1126-47-2)
• EPA Substance Registry System: 1,2-dithiolane-3,5-dicarboxylic acid (non-preferred name)(1126-47-2)

Safety Data

• Hazardous Substances Data: 1126-47-2(Hazardous Substances Data)

Usage

General Description

1,2-dithiolane-3,5-dicarboxylic acid is a chemical compound with a non-preferred name that belongs to the class of organic compounds known as dithiolanes. It is a derivative of dithiolane and contains carboxylic acid functional groups. 1,2-dithiolane-3,5-dicarboxylic acid (non-preferred name) has potential applications in the pharmaceutical and chemical industries due to its unique structure and properties. However, detailed information about its specific uses and properties is limited, and further research may be needed to fully understand its potential applications.

Upstream product

• 1126-47-2 rac-1,2-dithiolane-3,5-dicarboxylic acid 

Downstream Products

• 19308-03-3 L_g-threo-2,4-dimercapto-glutaric acid 
• 19308-03-3 D_g-threo-2,4-dimercapto-glutaric acid 
• 1126-47-2 (S)-trans-[1,2]dithiolane-3,5-dicarboxylic acid 
• 19308-03-3 rac-2,4-dimercaptoglutaric acid 

Relevant articles and documents

Structural characterization of 1,3-propanedithiols that feature carboxylic acids: Homologues of mercury chelating agents

The molecular structures of a series of 1,3-propanedithiols that contain carboxylic acid groups, namely rac- and meso-2,4-dimercaptoglutaric acid (H 4DMGA) and 2-carboxy-1,3-propanedithiol (H3DMCP), have been determined by X-ray diffraction. Each compound exhibits two centrosymmetric intermolecular hydrogen bonding interactions between pairs of carboxylic acid groups, which result in a dimeric structure for H3DMCP and a polymeric tape-like structure for rac- and meso-H4DMGA. Significantly, the hydrogen bonding motifs observed for rac- and meso-H 4DMGA are very different to those observed for the 1,2-dithiol, rac-2,3-dimercaptosuccinic acid (rac-H4DMSA), in which the two oxygen atoms of each carboxylic acid group hydrogen bond to two different carboxylic acid groups, thereby resulting in a hydrogen bonded sheet-like structure rather than a tape. Density functional theory calculations indicate that 1,3-dithiolate coordination to mercury results in larger S-Hg-S bond angles than does 1,2-dithiolate coordination, but these angles are far from linear. As such, κ2-S2 coordination of these dithiolate ligands is expected to be associated with mercury coordination numbers of greater than two. In vivo studies demonstrate that both rac-H4DMGA and H 3DMCP reduce the renal burden of mercury in rats, although the compounds are not as effective as either 2,3-dimercaptopropane-1-sulfonic acid (H3DMPS) or meso-H4DMSA.