1126138-12-2

Usage

Uses

Used in Organic Synthesis:
2,4,6-TriMethyl-5-nitrobenzene-d11 is used as a synthetic intermediate for the production of various organic compounds. Its unique structure allows it to serve as a building block in the synthesis of complex molecules, which can be further modified or functionalized to create a wide range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4,6-TriMethyl-5-nitrobenzene-d11 is used as a key component in the development of new drugs. Its chemical properties make it a valuable starting material for the synthesis of various drug candidates, particularly those with potential applications in the treatment of various diseases and medical conditions.
Used in Chemical Research:
2,4,6-TriMethyl-5-nitrobenzene-d11 is also employed in chemical research as a model compound for studying various reaction mechanisms and exploring new synthetic routes. Its deuterated nature makes it particularly useful in studying the kinetics and isotope effects of different chemical reactions, contributing to a deeper understanding of organic chemistry.
Used in Material Science:
In the field of material science, 2,4,6-TriMethyl-5-nitrobenzene-d11 can be used as a precursor for the development of novel materials with specific properties. Its unique structure and deuterium content can be exploited to create materials with enhanced stability, reactivity, or other desirable characteristics for various applications, such as in electronics, coatings, or adhesives.

Upstream product

• 69441-16-3 perdeuterio-1,3,5-trimethylbenzene 

Downstream Products

• 1126138-13-3 d₁₁-2,4,6-trimethylaniline 
• 1126138-21-3 d₂₂-2,4,6-trimethyl-N-[2-[(2,4,6-trimethylphenyl) imino]ethylidene]aniline 

Relevant academic research and scientific papers

Iridium(III) hydrido N-heterocyclic carbene-phosphine complexes as catalysts in magnetization transfer reactions

The hyperpolarization (HP) method signal amplification by reversible exchange (SABRE) uses para-hydrogen to sensitize substrate detection by NMR. The catalyst systems [Ir(H)2(IMes)(MeCN)2(R)]BF4 and [Ir(H)2(IMes)(py)2(R)]BF4 [py = pyridine; R = PCy3 or PPh3; IMes = 1,3-bis(2,4,6-trimethylphenyl) imidazol-2-ylidene], which contain both an electron-donating N-heterocyclic carbene and a phosphine, are used here to catalyze SABRE. They react with acetonitrile and pyridine to produce [Ir(H)2(NCMe)(py)(IMes)(PPh 3)]BF4 and [Ir(H)2(NCMe)(py)(IMes)(PCy 3)]BF4, complexes that undergo ligand exchange on a time scale commensurate with observation of the SABRE effect, which is illustrated here by the observation of both pyridine and acetonitrile HP. In this study, the required symmetry breaking that underpins SABRE is provided for by the use of chemical inequivalence rather than the previously reported magnetic inequivalence. As a consequence, we show that the ligand sphere of the polarization transfer catalyst itself becomes hyperpolarized and hence that the high-sensitivity detection of a number of reaction intermediates is possible. These species include [Ir(H)2(NCMe)(py)(IMes)(PPh3)] BF4, [Ir(H)2(MeOH)(py)(IMes)(PPh3)]BF 4, and [Ir(H)2(NCMe)(py)2(PPh 3)]BF4. Studies are also described that employ the deuterium-labeled substrates CD3CN and C5D5N, and the labeled ligands P(C6D5)3 and IMes-d22, to demonstrate that dramatically improved levels of HP can be achieved as a consequence of reducing proton dilution and hence polarization wastage. By a combination of these studies with experiments in which the magnetic field experienced by the sample at the point of polarization transfer is varied, confirmation of the resonance assignments is achieved. Furthermore, when [Ir(H)2(pyridine-h5)(pyridine-d5)(IMes) (PPh3)]BF4 is examined, its hydride ligand signals are shown to become visible through para-hydrogen-induced polarization rather than SABRE.

Thermal decomposition modes for four-coordinate ruthenium phosphonium alkylidene olefin metathesis catalysts

The four-coordinate ruthenium phosphonium alkylidenes 1-Cy and 1-iPr, differing in the substituent on the phosphorus center, were observed to decompose thermally in the presence of 1,1-dichloroethylene to produce [H 3CPR3][Cl]. The m