112633-43-9

Upstream product

• 1072-67-9 5-methylisoxazol-3-ylamine 
• 89-95-2 2-methyl-benzyl alcohol 
• 90-02-8 salicylaldehyde 

Downstream Products

• 119485-44-8 C₂₈H₂₂N₂O₄ 
• 298216-14-5 2-[(5-methyl-3-isoxazolyl)amino]methylphenol 
• 1233715-20-2 C₁₉H₁₆ClN₃O₃ 
• 1233715-19-9 C₁₉H₁₆BrN₃O₃ 
• 1233715-18-8 C₂₀H₁₉N₃O₄ 
• 1233715-17-7 C₂₀H₁₉N₃O₃ 
• 1233715-10-0 C₁₉H₁₇N₃O₃ 
• 1233715-06-4 C₁₈H₁₆ClN₃O₃ 
• 1233715-05-3 C₁₈H₁₆BrN₃O₃ 
• 1233715-04-2 C₁₉H₁₉N₃O₄ 
• 1233715-03-1 C₁₉H₁₉N₃O₃ 
• 1233714-96-9 N₂-(2-hydroxybenzyl)-N₂-(5-methyl-3-isoxazolyl)-N₁-phenylurea 

Relevant academic research and scientific papers

Unusual products of reaction between aminoisoxazoles and aromatic aldehydes

The reaction between primary amine and aldehyde usually leads to a Schiff base. In this work, we present the results of research (NMR, ATR-FTIR, UV–Vis, and X-ray) of products obtained in the reaction of 5-methyl-3-aminoisoxazole (3AMI) or 3-methyl-5-amin

A facile and simple synthesis of novel isoxazolyl benzo[f][l,4]oxazepin-3-(2H)-ones and their antimicrobial activity

A series of novel isoxazolyl benzo[f][l,4]oxazepin-3-(2H)-ones (9a-h) have been synthesized by adopting a facile and. simple methodology. The reaction of 3-arnino-5-methylisoxazole (5) with salicylaldehydes (6), followed by reduction with " NaBH4, and in situ chloroacetylation and cyclization with chloroacetyl chloride and triethyl amine affords isoxazolyl benzo[f][l,4]oxazepin-3-(2H)-ones (9a-h). The newly synthesized compounds (7-9) have been characterized by spectral (IR, 1H and 13C NMR, and HRMS) data. The title compounds (9a-h) have been evaluated for their in vitro antimicrobial activity against different bacterial and fungal strains. Compounds 9b, 9f and 9g show excellent antimicrobial activity, when compared to the respective standard drugs.

Synthesis of novel isoxazolyl 3,4,5,6-tetrahydro-2H-1,3,5-benzoxadiazocin- 4-ones as possible biodynamic agents

Synthesis of new isoxazolyl 1,3,5-benzoxadiazocin-4-ones 5 has been accomplished by condensation of 3-amino-5-methylisoxazole 1 with salicylaldehydes, followed by reduction, treatment with arylisocyanates and subsequent ring closure in presence of formald

A simple method for the synthesis of 5-isoxazolyl-4-thioxo-1,3,5- benzoxadiazocines

Synthesis of novel isoxazolyl 1,3,5-benzoxadiazocines 5 has been accomplished by condensation of 3-amino-5-methylisoxazole 1 with salicylaldehydes, followed by reduction, treatment with arylisothio-cyanates, and subsequent ring closure in the presence of

Solvent-free syntheses of salicylaldimines assisted by microwave irradiation

A microwave-assisted condensation of salicylaldehyde and aryl amines without solvent were efficiently performed to form a series of salicylaldimines in high yields, which were confirmed by IR, 1H NMR, 13C NMR and elemental analyses. The microwave-assisted condensation provided a convenient environmental-friendship methodology for syntheses of Schiff-base in organic syntheses.