298216-14-5

Basic information

• Product Name: 2-([(5-METHYL-3-ISOXAZOLYL)AMINO]METHYL)BENZENOL
• Synonyms: 2-([(5-METHYL-3-ISOXAZOLYL)AMINO]METHYL)BENZENOL;2-{[(5-methyl-1,2-oxazol-3-yl)amino]methyl}phenol
• CAS NO: 298216-14-5
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 204.23
• Mol File: 298216-14-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-([(5-METHYL-3-ISOXAZOLYL)AMINO]METHYL)BENZENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-([(5-METHYL-3-ISOXAZOLYL)AMINO]METHYL)BENZENOL(298216-14-5)
• EPA Substance Registry System: 2-([(5-METHYL-3-ISOXAZOLYL)AMINO]METHYL)BENZENOL(298216-14-5)

Safety Data

• Hazardous Substances Data: 298216-14-5(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 112633-43-9 2-[(5-methyl-3-isoxazolyl)imino]methylphenol 

Downstream Products

• 1153622-53-7 N-(2-hydroxybenzyl)-N-(5-methyl-3-isoxazolyl)-N'-phenylthiourea 
• 1153622-55-9 N'-(4-chlorophenyl)-N-(2-hydroxybenzyl)-N-(5-methyl-3-isoxazolyl)thiourea 
• 1153622-58-2 N-(2-hydroxybenzyl)-N-(5-methyl-3-isoxazolyl)-N'-(4-methylphenyl)thiourea 
• 1153622-56-0 N'-(4-bromophenyl)-N-(2-hydroxybenzyl)-N-(5-methyl-3-isoxazolyl)thiourea 
• 1233715-10-0 C₁₉H₁₇N₃O₃ 
• 1233715-17-7 C₂₀H₁₉N₃O₃ 
• 1233715-18-8 C₂₀H₁₉N₃O₄ 
• 1233715-19-9 C₁₉H₁₆BrN₃O₃ 
• 1233715-20-2 C₁₉H₁₆ClN₃O₃ 
• 1233715-06-4 C₁₈H₁₆ClN₃O₃ 
• 1233714-96-9 N₂-(2-hydroxybenzyl)-N₂-(5-methyl-3-isoxazolyl)-N₁-phenylurea 
• 1233715-03-1 C₁₉H₁₉N₃O₃ 
• 1233715-04-2 C₁₉H₁₉N₃O₄ 
• 1233715-05-3 C₁₈H₁₆BrN₃O₃ 

Relevant articles and documents

A facile and simple synthesis of novel isoxazolyl benzo[f][l,4]oxazepin-3-(2H)-ones and their antimicrobial activity

A series of novel isoxazolyl benzo[f][l,4]oxazepin-3-(2H)-ones (9a-h) have been synthesized by adopting a facile and. simple methodology. The reaction of 3-arnino-5-methylisoxazole (5) with salicylaldehydes (6), followed by reduction with " NaBH4, and in situ chloroacetylation and cyclization with chloroacetyl chloride and triethyl amine affords isoxazolyl benzo[f][l,4]oxazepin-3-(2H)-ones (9a-h). The newly synthesized compounds (7-9) have been characterized by spectral (IR, 1H and 13C NMR, and HRMS) data. The title compounds (9a-h) have been evaluated for their in vitro antimicrobial activity against different bacterial and fungal strains. Compounds 9b, 9f and 9g show excellent antimicrobial activity, when compared to the respective standard drugs.

A simple method for the synthesis of 5-isoxazolyl-4-thioxo-1,3,5- benzoxadiazocines

Synthesis of novel isoxazolyl 1,3,5-benzoxadiazocines 5 has been accomplished by condensation of 3-amino-5-methylisoxazole 1 with salicylaldehydes, followed by reduction, treatment with arylisothio-cyanates, and subsequent ring closure in the presence of