1126367-34-7

Basic information

• Product Name: 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE
• Synonyms: 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE;Benzene, 1-broMo-2-chloro-4-Methyl-5-nitro-
• CAS NO: 1126367-34-7
• Molecular Formula: C₇H₅BrClNO₂
• Molecular Weight: 250.48
• Mol File: 1126367-34-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 303.6±37.0 °C(Predicted)
• Appearance: /
• Density: 1.719±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE(1126367-34-7)
• EPA Substance Registry System: 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE(1126367-34-7)

Safety Data

• Hazardous Substances Data: 1126367-34-7(Hazardous Substances Data)

Usage

General Description

1-Bromo-2-chloro-4-methyl-5-nitro-benzene is a synthetic, organic compound that is categorized as an aromatic halogen compound. It is characterized by a collection of chemical groups - a bromo, a chloro, a methyl, and a nitro - attached to a benzene ring, which is a hexagonal ring of carbon atoms. It has the molecular formula of C7H5BrClNO2 and molecular weight of 284.484 g/mol. It is often used in organic synthesis and various chemical research. The compound is generally seen as a yellow solid, and while specifics on its toxicity aren't widely reported or known, it should be handled with care like many synthetic, halogenated benzene derivatives which have potential to be hazardous.

Upstream product

• 6627-51-6 1-bromo-2-chloro-4-methylbenzene 

Downstream Products

• 1126367-88-1 5-bromo-4-chloro-2-methylaniline 
• 1126368-31-7 N-[4-chloro-2-methyl-5-(1-methyl-1H-imidazol-2-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide 
• 1126368-35-1 N-[4-chloro-5-(1,2-dimethyl-1H-imidazol-4-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide 
• 1126366-38-8 N-[4-chloro-2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide 
• 1126368-33-9 N-[4-chloro-5-(1H-imidazol-2-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide 
• 1126367-36-9 N-(4-chloro-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-(pyridin-2-ylmethoxy)benzamide 
• 1126369-57-0 N-(5-bromo-4-chloro-2-methylphenyl)-4-(pyridin-2-ylmethoxy)benzamide 

Relevant articles and documents

N-HETEROARYL INDAZOLE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

The present invention is directed to substituted certain N-heteroaryl indazole derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, X, Y, and Z are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of diseases, such as Parkinson's disease, in which LRRK-2 kinase is involved.

COMPOUNDS

Disclosed are novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, compositions containing them and their use in the treatment of or prevention of diseases characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis(ALS).