1126602-63-8Relevant articles and documents
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents
Gangjee, Aleem,Zhao, Ying,Ihnat, Michael A.,Thorpe, Jessica E.,Bailey-Downs, Lora C.,Kisliuk, Roy L.
, p. 4217 - 4225 (2012/09/08)
We designed, synthesized and evaluated 13 novel tricyclic indeno[2,1-d]pyrimidines as RTK inhibitors. These analogues were synthesized via a Dieckmann condensation of 1,2-phenylenediacetonitrile followed by cyclocondensation with guanidine carbonate to af