1126624-05-2

Upstream product

• 1126623-99-1 (E)-4-methyl-1-phenylhexa-1,4,5-trien-3-ol 

Downstream Products

• 1269626-84-7 3-((1H-indol-3-yl)methyl)-2-methyl-4-phenylcyclopent-2-enone 
• 1269626-90-5 (1E,4Z)-5-(1H-indol-3-yl)-4-methyl-1-phenylhexa-1,4-dien-3-one 
• 1269626-87-0 2-methyl-3-((2-methyl-1H-indol-3-yl)methyl)-4-phenylcyclopent-2-enone 
• 1269626-86-9 2-methyl-3-((1-methyl-1H-indol-3-yl)methyl)-4-phenylcyclopent-2-enone 
• 1269626-77-8 (1E,4Z)-4-methyl-1-phenyl-5-(1H-pyrrol-2-yl)hexa-1,4-dien-3-one 
• 1269626-88-1 3-((1,2-dimethyl-1H-indol-3-yl)methyl)-2-methyl-4-phenylcyclopent-2-enone 
• 1269626-85-8 3-((5-methoxy-1H-indol-3-yl)methyl)-2-methyl-4-phenylcyclopent-2-enone 
• 1269626-74-5 2-methyl-3-((1-(methylsulfonyl)-1H-pyrrol-2-yl)methyl)-4-phenylcyclopent-2-enone 
• 1269626-73-4 tert-butyl 2-((2-methyl-3-oxo-5-phenylcyclopent-1-enyl)methyl)-1H-pyrrole-1-carboxylate 
• 1269626-76-7 2-methyl-4-phenyl-3-((1-(para-toluenesufonyl)-1H-pyrrol-2-yl)methyl)cyclopent-2-enone 

Relevant academic research and scientific papers

Trapping the oxyallyl cation intermediate derived from the Nazarov cyclization of allenyl vinyl ketones with nitrogen heterocycles

The cationic intermediate of the Lewis acid-initiated Nazarov cyclization of an allenyl vinyl ketone (AVK) was trapped by pyrroles and indoles. The yields ranged from modest to high (up to 93%), and in both cases, only two of the three possible products w

Synthesis of 5-hydroxycyclopent-2-Enones from allenyl vinyl ketones via an interrupted Nazarov cyclization

Treatment of an allenyl vinyl ketone with trifluoroacetic acid leads to Nazarov cyclization, and the intermediate carbocation is trapped efficiently by trifluoroacetate. Hydrolysis of the ester with methanol and basic alumina provides, in good to excellen