112673-26-4

Basic information

• Product Name: (r-4,c-2,t-5)-N-methyl-2-p-nitrophenyl-4,5-trimethylenetetrahydro-1,3-oxazine
• CAS NO: 112673-26-4
• Molecular Weight: 262.309
• Mol File: 112673-26-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (r-4,c-2,t-5)-N-methyl-2-p-nitrophenyl-4,5-trimethylenetetrahydro-1,3-oxazine(CAS DataBase Reference)
• NIST Chemistry Reference: (r-4,c-2,t-5)-N-methyl-2-p-nitrophenyl-4,5-trimethylenetetrahydro-1,3-oxazine(112673-26-4)
• EPA Substance Registry System: (r-4,c-2,t-5)-N-methyl-2-p-nitrophenyl-4,5-trimethylenetetrahydro-1,3-oxazine(112673-26-4)

Safety Data

• Hazardous Substances Data: 112673-26-4(Hazardous Substances Data)

Upstream product

• 4492-47-1 (+/-)-trans-2-(hydroxymethyl)cyclopentylamine 
• 555-16-8 4-nitrobenzaldehdye 
• 98430-01-4 trans-N-methyl-2-hydroxymethylcyclopentylamine 

Relevant articles and documents

STEREOCHEMICAL STUDIES 130 SATURATED HETEROCYCLES 132; SYNTHESIS AND RING-CHAIN TAUTOMERISM OF STEREOISOMERIC 1,3-OXAZINES CONDENSED WITH THE CYCLOPENTANE RING

Trough condensation of cis-2-hydroxymethylcyclopentylamine (3) and cis-2-aminomethylcyclopentanol (5) with aromatic aldehydes, tautomeric mixtures of 1,3-oxazines and open-chain Schiff bases were obtained.The two series of compounds (4a-f, 6a-f) gave satisfactory linear collerations corresponding to log Kx=k?++log KX=H (k=0.76+/-0.04 as shown earlier).The ring form of the corresponding trans derivatives is present in a fairly low amount, because of the strain in the trans fusion of the cyclopentane and the sixmembered hetero ring.N-Methyl substitution makes the ring form in the latter compounds stable, resulting in oxazines 12 and 14.All the cyclizations in question occurred stereospecifically.