4492-47-1

Usage

Uses

Used in Pharmaceutical Synthesis:
2-AminocyclopentaneMethanol is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence in the molecular structure allows for the development of new drugs with potential therapeutic applications.
Used in the Preparation of 2-Azabicyclo[2.2.1]Heptanes:
2-AminocyclopentaneMethanol is used as a starting material for the preparation of 2-azabicyclo[2.2.1]heptanes, which are a class of bicyclic compounds with potential applications in the pharmaceutical industry. These compounds can exhibit a range of biological activities, making them valuable for the development of new drugs.

InChI:InChI=1/C6H13NO/c7-6-3-1-2-5(6)4-8/h5-6,8H,1-4,7H2

Upstream product

• 3814-46-8 ACPA 
• 245115-25-7 (1R,2R)-2-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid 
• 228422-24-0 2-hydroxymethylcyclopentane carboxamide 
• 3205-94-5 1-cyclopentene-1,2-dicarboxylic anhydride 
• 113428-55-0 hexahydro-cyclopenta[c]furan-1-one 
• 821-41-0 5-Hexen-1-ol 
• 764-59-0 hex-5-en-1-al 
• 152495-65-3 C₁₃H₁₇NO 

Downstream Products

• 117720-32-8 cis-cyclopentanol<1,3>-thiazine 
• 117720-36-2 (4aR,7aS)-Hexahydro-cyclopenta[d][1,3]oxazin-(2Z)-ylidene-phenyl-amine 
• 117720-22-6 1-((1S,2R)-2-Hydroxymethyl-cyclopentyl)-3-phenyl-thiourea 
• 112673-02-6 (2S,4aR,7aS)-2-p-Tolyl-octahydro-cyclopenta[d][1,3]oxazine 
• 112673-26-4 (r-4,c-2,t-5)-N-methyl-2-p-nitrophenyl-4,5-trimethylenetetrahydro-1,3-oxazine 
• 117720-32-8 trans-cyclopentanol<1,3>-thiazine 
• 117720-36-2 (4aS,7aS)-Hexahydro-cyclopenta[d][1,3]oxazin-(2Z)-ylidene-phenyl-amine 
• 117720-22-6 1-((1S,2S)-2-Hydroxymethyl-cyclopentyl)-3-phenyl-thiourea 
• 136315-70-3 (±)-cis-2-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid 
• 57043-00-2 (1RS,2SR)-cispentacin 
• 112673-04-8 Dimethyl-[(2S,4aR,7aS)-4-(octahydro-cyclopenta[d][1,3]oxazin-2-yl)-phenyl]-amine 
• 112673-03-7 (2S,4aR,7aS)-2-(4-Methoxy-phenyl)-octahydro-cyclopenta[d][1,3]oxazine 

Relevant academic research and scientific papers

TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS

The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.

SUBSTITUTED CYCLOALKYLAMINE DERIVATIVES AND THEIR USE AS CALCIUM CHANNEL ANTAGONISTS

A method of treatment of a condition or disease related to the accumulation of calcium in the brain cells of a mammal which comprises administering to a subject in need thereof an effective amount of a compound of formula (I), wherein X is O, S, C=O or a bond; p and q are independently 0-4; R. sup.1 and R 2 are each independently selected from the group consisting of hydrogen, C 1-6 alkyl, C 3-6 cycloalkyl or C 3-6 cycloalkylC 1-4 alkyl; n is 1, 2, 3 or 4; and Ar is phenyl optionally substituted by 1 to 3 substituents selected from; halo, C 1-4 alkyl, C 1-4 alkoxy, C 1-2 alkylenedioxy, trifluoromethyl, trifluoromethoxy, CN, NO 2, amino, mono-or di-alkylamino and Ph(Alk 1) r Y(Alk 2) s--where Ph is optionally substituted phenyl, Y is a bond, oxygen or a carbonyl group, Alk 1 and Alk 2 are independently C. sub.1-4 alkyl which may be straight or branched and r and s are independently 0 or 1, provided that the length of (Alk 1) r Y(Alk 2) s does not exceed 5 atoms, and pharmaceutically acceptable salts thereof; in the manufacture of a medicament for the treatment of a disorder wherein a calcium channel antagonist is indicated, e.g. ischaemic stroke. Certain novel compounds within formula (I) are also claimed.

Synthesis and biological activity of some 2-aminopurine carbonucleosides

A series of new one two substituted carbonucleoside analogues (OTC) of purine was synthesized and evaluated against cytomegalovirus and varicella- zoster virus in human embryonic lung (HEL) cells.

Synthesis of racemic and optically active cispentacin (FR109615) using intramolecular nitrone-olefin cycloaddition

Synthesis of racemic and optically active cispentacin ((-)-1) is described. Intramolecular nitrone-olefin cycloaddition of the alkenyl nitrone 7 gave cis-isoxazolidine (±)-8, which was transformed into (±)-1 by sequential reactions involving catalytic hyd