1126906-70-4Relevant academic research and scientific papers
Highly active rhodium catalyst with electron-poor diphosphine enables efficient synthesis of chiral 4-aryl-δ-lactones
Korenaga, Toshinobu,Maenishi, Ryota,Osaki, Kazutaka,Sakai, Takashi
, p. 157 - 162 (2010)
Chiral 4-aryl-δ-lactones could be synthesized efficiently with high enantioselectivity through asymmetric 1,4-addition of arylboronic acid to α,β-unsaturated lactones using Rh catalyst including electron-poor diphosphine (MeO-F12-BIPHEP) at room temperature for 1 h. In particular, our catalytic system proved to be applicable to relatively large coumarin analogues, giving optically pure 4-phenylchroman-2-one analogues in a short time.
Design of N-sulfinyl homoallylic amines as novel sulfinamide-olefin hybrid ligands for asymmetric catalysis: Application in Rh-catalyzed enantioselective 1,4-additions
Jin, Shen-Shuang,Wang, Hui,Xu, Ming-Hua
supporting information; experimental part, p. 7230 - 7232 (2011/08/09)
Here we show that simple and readily available chiral sulfinamide-olefins can display great catalytic activities and enantioselectivities in rhodium-catalyzed 1,4-addition reactions. This study represent the first example of chiral sulfur-based olefin ligand class for transition metal-catalyzed asymmetric transformation.
Base-base bifunctional catalysis: A practical strategy for asymmetric Michael addition of malonates to α,β-unsaturated aldehydes
Wang, Yongcan,Li, Pengfei,Liang, Xinmiao,Yea, Jinxing
supporting information; experimental part, p. 1383 - 1389 (2009/06/18)
Lewis base-Bronsted base bifunctional catalysis is a novel and practical strategy for the asymmetric Michael addition. The addition of malonates to a series of α,β-unsaturated aldehydes can take place under base-base bifunctional catalytic conditions using 0.5-5 mol% of (S)-2-[diphenyl(trimethylsilyloxy) methyl]pyrrolidine as catalyst and 5-30 mol% of lithium 4-fluorobenzoate as additive base with up to 99% ee.
